T involutional depression and that electro-convulsive therapy (ECT) was “very much more effective.” They also argued that the only group of patients who benefited from endocrinological treatment were cases of anxiety arising during the menopause (Sargant Slater, 1944, p. 131). In part, their rejection of glandular therapies was conditioned by enthusiasm for two radical interventions: ECT and prefrontal leucotomy. In fact, it is Golla who holds the dubious distinction of authorizing the first prefrontal leucotomy performed in the United Kingdom, which took place at the Burden Institute in October 1941 (Golla, 1943). In addition, the Maudsley move away from endocrinological treatments was impacted by the fact that it was difficult to source quality hormones for the purposes of research following the outbreak of the Second World War. Maudsley doctors then began to focus on the neurochemistry of the brain rather than the study of hormones or “chemical messengers” which traversed the whole body before having an impact on the mind.JOURNAL OF THE HISTORY OF THE BEHAVIORAL SCIENCES DOI 10.1002/jhbsBONNIE EVANS AND EDGAR JONESCONCLUSION The influence of British psychology and instinct theory, in particular the work of William McDougall, was clearly evident in the treatment of patients at the Maudsley Hospital during the 1920s and the early 1930s. Early Maudsley practitioners such as Dawson viewed the human mind as the by-product of more fundamental biological processes and reflex actions which drove the human organism. Dawson claimed that the human organism responded to environmental stimuli at four different levels. The “primitive, chemical level” which included the endocrine system; the “reflex action” which was driven by nervous response; the “instinctive action” where consciousness began to play a part; and the “volitional action” which was directed by the conscious mind and often conflicted with reactions from the lower levels (Dawson, 1924, pp. 5?). In his research at the Maudsley laboratories, Mott also emphasized the need to consider the whole body when addressing psychiatric problems We now generally recognise the brain as the seat of the psyche, but the functions of the mind are dependent upon the whole body and the harmonious interaction of all its parts. Maudsley doctors’ interest in the use of glandular extracts to treat psychiatric disorder stemmed from an interest in the role of hormones as chemical messengers. They thought that if one could alter bodily reflexes and responses at their most primitive, chemical, level then this could also enable mental adjustment. Little was known of the exact chemical processes which the administration of organ extracts provoked within the body or brain, though interest into these chemical processes did grow in the Maudsley laboratories by the 1930s. Focusing on the United States, Jack Pressman has explained the rise of lobotomy and intrusive Trichostatin A chemical information medical interventions in psychiatric illness as a response to a growing urgency among psychiatric professionals to establish their discipline as a legitimate branch of medicine in the late 1930s. In Britain, Sargant, Slater, and others’ enthusiasm for such treatments was also driven by their desire to establish psychiatry as a medical science and to show that radical transformations were get PX-478 possible. In 1957, Sargant appeared in a documentary produced by the British Broadcasting Corporation (BBC) entitled “The Hurt Mind: Physical Treatments” which advocated th.T involutional depression and that electro-convulsive therapy (ECT) was “very much more effective.” They also argued that the only group of patients who benefited from endocrinological treatment were cases of anxiety arising during the menopause (Sargant Slater, 1944, p. 131). In part, their rejection of glandular therapies was conditioned by enthusiasm for two radical interventions: ECT and prefrontal leucotomy. In fact, it is Golla who holds the dubious distinction of authorizing the first prefrontal leucotomy performed in the United Kingdom, which took place at the Burden Institute in October 1941 (Golla, 1943). In addition, the Maudsley move away from endocrinological treatments was impacted by the fact that it was difficult to source quality hormones for the purposes of research following the outbreak of the Second World War. Maudsley doctors then began to focus on the neurochemistry of the brain rather than the study of hormones or “chemical messengers” which traversed the whole body before having an impact on the mind.JOURNAL OF THE HISTORY OF THE BEHAVIORAL SCIENCES DOI 10.1002/jhbsBONNIE EVANS AND EDGAR JONESCONCLUSION The influence of British psychology and instinct theory, in particular the work of William McDougall, was clearly evident in the treatment of patients at the Maudsley Hospital during the 1920s and the early 1930s. Early Maudsley practitioners such as Dawson viewed the human mind as the by-product of more fundamental biological processes and reflex actions which drove the human organism. Dawson claimed that the human organism responded to environmental stimuli at four different levels. The “primitive, chemical level” which included the endocrine system; the “reflex action” which was driven by nervous response; the “instinctive action” where consciousness began to play a part; and the “volitional action” which was directed by the conscious mind and often conflicted with reactions from the lower levels (Dawson, 1924, pp. 5?). In his research at the Maudsley laboratories, Mott also emphasized the need to consider the whole body when addressing psychiatric problems We now generally recognise the brain as the seat of the psyche, but the functions of the mind are dependent upon the whole body and the harmonious interaction of all its parts. Maudsley doctors’ interest in the use of glandular extracts to treat psychiatric disorder stemmed from an interest in the role of hormones as chemical messengers. They thought that if one could alter bodily reflexes and responses at their most primitive, chemical, level then this could also enable mental adjustment. Little was known of the exact chemical processes which the administration of organ extracts provoked within the body or brain, though interest into these chemical processes did grow in the Maudsley laboratories by the 1930s. Focusing on the United States, Jack Pressman has explained the rise of lobotomy and intrusive medical interventions in psychiatric illness as a response to a growing urgency among psychiatric professionals to establish their discipline as a legitimate branch of medicine in the late 1930s. In Britain, Sargant, Slater, and others’ enthusiasm for such treatments was also driven by their desire to establish psychiatry as a medical science and to show that radical transformations were possible. In 1957, Sargant appeared in a documentary produced by the British Broadcasting Corporation (BBC) entitled “The Hurt Mind: Physical Treatments” which advocated th.
