Amino acids and derivatives, amines and polyamines and carbohydrates. An added group designated as “others” in Figure gathers metabolites that have been putatively assigned to various chemical groups including organic acids, xanthonoids and benzoxazinoids. Surprisingly, only 1 benzoxazinoid derivative, the methoxybenzoxazolinHone, was putatively identified inside the thirteen research utilized for this overview, although these cereal metabolites have already been extensively studied for their antimicrobial efficiency and their key function in defense of maize against a variety of pathogens ,. The majority of the putatively identified metabolites derive from the shikimate, acetatemevalonate and methylerythritol phosphate pathways, that are the 3 most important plant metabolic pathways involved in cereal 
defense against pathogens and pests . According to Gunnaiah and Kushalappa , the chemical defense against fungal pathogens which includes DON making Fusarium species is linked to 3 primary mechanisms of resistancecell wall reinforcement by way of the deposition of lignin, production of antimicrobial compounds and precise induction of defense signaling pathways.Int. J. Mol. SciTable . Overview of metabolomic studies addressing the mechanisms of Fusarium head blight (FHB) resistance in wheat and barley.Pathosystem Plant Wheat. cultivarssusceptible (Roblin); resistant (Sumai) Wheat. genotypes with distinctive levels of FHB resistance Pathogen A part of the Plant; Stage of Inoculation ab; Harvesting a Spikelets; Inoculation GS (anthesis); Harvested at hai Leaf and stem; no inoculation 
Harvested at days of increasing Spikelets; Inoculation GS (anthesis); Harvested at hai Technology Database Putatively Identified Metabolites Linked to FHB Resistance Most important Chemical Groups Carbohydrates; Fatty acids; Phenylpropanoids Amines; Amino acids; Carbohydrates Amino acids; Carbohydrates; Fatty acids; Organic acids; Phenylpropanoids; Polyamines Amino acids; Carbohydrates; Fatty acids; Organic acids; Phnelypropanoids; Polyamines Amino acids; Fatty acids; PhenylpropanoidsReferenceF. graminearumGCMSNISTnoneH NMRIdentification by spiking with standardsWheat. cultivars with distinct levels of FHB resistanceF. graminearumGCMSGMD; NISTWheat. cultivarssusceptible (Roblin); resistant (Sumai)F. graminearum or DONSpikelets; Inoculation GS (anthesis); Harvested at haiGCMSGMD; NISTBarley. cultivarssusceptible (Stander); resistant (Chevron)F. graminearumSpikelets; Inoculation GS ; Harvested at haiLCESILTQOrbitrapMETLIN; PubChem; Mikamycin B KNApSAcK; PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/7654926 HMDB; MoToInt. J. Mol. SciTable . Cont.Pathosystem Plant Barley. genotypesresistant (Chevron other people); susceptible (Stander) Barley. genotypessusceptible; resistant Pathogen Part of the Plant; Stage of Inoculation ab; Harvesting a Spikelets; Inoculation GS ; Harvested at hai Spikelets; Inoculation at GS (anthesis to early milk stage); NA Spikelets; Inoculation at GS (anthesis to early milk stage); Harvested at hai Technologies Database Putatively Identified Metabolites Linked to FHB Resistance Primary Chemical Groups Fatty acids; Phenylpropanoids; TerpenoidsReferenceF. graminearumLCESILTQOrbitrapNot citedF. graminearumLCESILTQOrbitrapMETLIN; KNApSAcK; MassBank; McGillMD; KEGG; HMDB Databases not cited Identification by spiking with standards METLIN; KNApSAcK; PMN; LIPIDMAPS; KEGG; McGillMDFatty acids; PhenylpropanoidsBarley. genotypessusceptible; resistantF. graminearumLCESILTQOrbitrapFatty acids; PhenylpropanoidsWheat. close to Isogenic Lines with susceptible and resistant alle.Amino acids and derivatives, amines and polyamines and carbohydrates. An added group designated as “others” in Figure gathers metabolites that have been putatively assigned to diverse chemical groups such as organic acids, xanthonoids and benzoxazinoids. Surprisingly, only 1 benzoxazinoid derivative, the methoxybenzoxazolinHone, was putatively identified inside the thirteen research applied for this overview, although these cereal metabolites have been extensively studied for their antimicrobial efficiency and their important role in defense of maize against numerous pathogens ,. Most of the putatively identified metabolites derive in the shikimate, acetatemevalonate and methylerythritol phosphate pathways, which are the 3 main plant metabolic pathways involved in cereal defense against pathogens and pests . As outlined by Gunnaiah and Kushalappa , the chemical defense against fungal pathogens including DON producing Fusarium species is linked to three main mechanisms of resistancecell wall reinforcement by means of the deposition of lignin, production of antimicrobial compounds and specific induction of defense signaling pathways.Int. J. Mol. SciTable . Overview of metabolomic research addressing the mechanisms of Fusarium head blight (FHB) resistance in wheat and barley.Pathosystem Plant Wheat. cultivarssusceptible (Roblin); resistant (Sumai) Wheat. genotypes with distinct levels of FHB resistance Pathogen Part of the Plant; Stage of Inoculation ab; Harvesting a Spikelets; Inoculation GS (anthesis); Harvested at hai Leaf and stem; no inoculation Harvested at days of SR9011 (hydrochloride) site growing Spikelets; Inoculation GS (anthesis); Harvested at hai Technologies Database Putatively Identified Metabolites Linked to FHB Resistance Principal Chemical Groups Carbohydrates; Fatty acids; Phenylpropanoids Amines; Amino acids; Carbohydrates Amino acids; Carbohydrates; Fatty acids; Organic acids; Phenylpropanoids; Polyamines Amino acids; Carbohydrates; Fatty acids; Organic acids; Phnelypropanoids; Polyamines Amino acids; Fatty acids; PhenylpropanoidsReferenceF. graminearumGCMSNISTnoneH NMRIdentification by spiking with standardsWheat. cultivars with various levels of FHB resistanceF. graminearumGCMSGMD; NISTWheat. cultivarssusceptible (Roblin); resistant (Sumai)F. graminearum or DONSpikelets; Inoculation GS (anthesis); Harvested at haiGCMSGMD; NISTBarley. cultivarssusceptible (Stander); resistant (Chevron)F. graminearumSpikelets; Inoculation GS ; Harvested at haiLCESILTQOrbitrapMETLIN; PubChem; KNApSAcK; PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/7654926 HMDB; MoToInt. J. Mol. SciTable . Cont.Pathosystem Plant Barley. genotypesresistant (Chevron other people); susceptible (Stander) Barley. genotypessusceptible; resistant Pathogen A part of the Plant; Stage of Inoculation ab; Harvesting a Spikelets; Inoculation GS ; Harvested at hai Spikelets; Inoculation at GS (anthesis to early milk stage); NA Spikelets; Inoculation at GS (anthesis to early milk stage); Harvested at hai Technology Database Putatively Identified Metabolites Linked to FHB Resistance Primary Chemical Groups Fatty acids; Phenylpropanoids; TerpenoidsReferenceF. graminearumLCESILTQOrbitrapNot citedF. graminearumLCESILTQOrbitrapMETLIN; KNApSAcK; MassBank; McGillMD; KEGG; HMDB Databases not cited Identification by spiking with standards METLIN; KNApSAcK; PMN; LIPIDMAPS; KEGG; McGillMDFatty acids; PhenylpropanoidsBarley. genotypessusceptible; resistantF. graminearumLCESILTQOrbitrapFatty acids; PhenylpropanoidsWheat. close to Isogenic Lines with susceptible and resistant alle.
