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Arsenic compounds are crucial drugs which have been used in both People’s Republic of China along with the Western globe for a lot more than two,000 years. Arsenic trioxide (As2O3) and arsenic sulfide (As4S4) had been discovered to possess exceptional anti-leukemic activity particularly against acute promyelocytic leukemia (APL).1? As2O3 features a synergistic effect when combined with all-trans-retinoic acid (ATRA). The exact mechanism of such synergistic impact on APL remains incompletely understood, even though it was found that thei.
