Equivalent to these reported in scientific literature ((i) the use of ionic doping with transition metals and (ii) the use of CaP from natural sources). The use of CaPs as an SPF-booster of organic UV filters has been reported in three patents, like the two most current ones [226,231,232]. An SPF-booster is an inorganic material that enhances the absorbing properties of organic filters by scattering the incident UV radiation. The usage of CaPs as boosters is amongst the most exciting approaches in their application for sun care cosmetics. 3.2.2. Skin Cleaners As mentioned just before, the skin is definitely an significant organ that protects us in the environment. For this reason, it truly is necessary to make sure the skin wellness also by using cleansers, which are surfactants employed to cut down sebum, take away make-up residuals or exogenous contaminants including sweat, pollution or dirt, and market standard exfoliation [23337]. Nevertheless, the repeated and prolonged interaction amongst these surfactants and also the proteins or lipids of stratum corneum could weaken the skin barrier function. The consequences of skin barrier degradation could be the after-wash tightness, which consists in rapid evaporation of water in the skin surface causing tightness, itch, dryness, irritation, or inflammation [238,239]. Therefore, there is a require to create cleansing systems that preserve and respect the skin barrier. The colloidal stability of Cyclosporin A Purity & Documentation cleansers is crucial and hence the use of stabilizing agents is needed. Within this regard, scientific literature reports considerable examples describing the benefits of applying solid particles (Pickering emulsions) [240,241] or all-natural minerals to attain the optimal emulsion stabilization for topical application purposes [24244]. In current years, the usage of solid particles was largely studied because they could present sustainable and Lithocholic acid custom synthesis eco-friendly solutions as stabilizers. Amongst each of the solid particles, calcium carbonate is normally employed for this objective [24547]. An example is reported by Marto et al. that has optimized a biocompatible Pickering emulsion formulation making use of calcium carbonate as a stabilizer [248]. Regarding CaP, to the greatest of our expertise, you will find no articles that describe these materials as stabilizers even when they could successfully substitute calcium carbonate in Pickering emulsions.Supplies 2021, 14,18 ofTable 3. List of patents about calcium phosphates as sunscreens.Ref. [223] [224] Title Coated powdery material and cosmetics containing precisely the same Sunscreen cosmetics Organic-inorganic composite powder, a preparation technique thereof, in addition to a use with the identical Sunscreen product comprising hydroxyapatite as physical filter Sunscreen Compositions Comprising Uniform, Rigid, Spherical, Nano porous Calcium Phosphate Particles and Approaches of Creating and Utilizing the identical UV-filters, system of creating the identical and their use in compositions, in particular sunscreens Physical solar filter consisting of substituted hydroxyapatite in an organic matrix Hydroxyapatite-transition metal composite preparation technique thereof and material for blocking ultraviolet rays and visible rays comprising precisely the same Physical sunscreen comprising hydroxyapatite or modified hydroxyapatite obtained from fisheries and aquaculture waste, course of action for its production and photoprotective compositions comprising it Calcium phosphate-folic acid composite particles, preparation method and application thereof Applicants Pola Chem Ind INC Fancl Corp Publication Year 2006 2009 D.