Sidential radon exposure [27]. Occupational exposure to higher concentrations of radon has also been demonstrated to raise the risk of lung cancer in non-smokers [28], along with the effects of occupational exposure to radon have also been described inside the mining industry [295].and in other workplaces [36]. Lately some research have discussed the so named “radon effect” as the long-term radon residential exposure estimates may very well be 20(S)-Hydroxycholesterol Data Sheet subject to errors as a consequence of distinct methodology for radon threat assessment and for retrospective assessment of smoking habits [379]. Likewise, other studies applying different statistical methods and thinking of extra carcinogenic risk things and risk modifiers or confounding aspects (gender, age, smoke habits, ultraviolet B (UVB), elevation of inhabited dwellings) found that the relative risk of lung cancer is independent of low radon concentration under about 800 Bq/m3 [402]. Nonetheless, it’s presently essential to comply using the reference levels established by the international and national regulatory agencies in compliance with all the As Low As Reasonably Achievable (ALARA) principle [24,43]. 1.1. Indoor Exposure to Radon The carcinogenic risk connected with buildings in the past was linked to the presence of asbestos [44]. To date, however, the concentrate is on indoor exposure to radon [70,459]. Reference Level. Following the results of many epidemiological research carried out in the final 20 years along with the consequential re-evaluation on the threat of lung cancer associated with exposure to radon in homes, in 2009, the Globe Wellness Organization [24] published the report “WHO Handbook on Indoor Radon: A Public Overall health Perspective”, in which it was suggested that nations possibly adopt a reference degree of one hundred Bq/m3 or, in any case, a reference level no Safranin Biological Activity greater than 300 Bq/m3 . In accordance with EURATOM, the National Radon Program and Apulian regional law (2016 n. 30; modified in 2017), at the same time as then also taken up nationally by the legislative decree 101/2020 the reference level indoor radon concentration in Apulia is 300 Bq/m3 [43,50,51]. Due to the stochastic partnership in between exposure to radon and cancer, prior studies have reported strategies for estimating lung cancer cases that happen to be attributable to radon [49]. 1.2. Earthquakes and Radon Anomalous increases in radon concentrations have already been determined before and just after the occurrence of earthquakes [526]. The 2012 Pollino (Calabria, Italy) seismic sequence, culminating in a moment magnitude (Mw) 5.2 earthquake on 25 October 2012, was investigated by exploiting data collected for the duration of a long-term continuous radon monitoring experiment performed in the epicentral location from late 2011 towards the end of 2014, this work has identified characteristic variations in radon exhalations throughout the preparation processes of huge earthquakes [57]. The necessity of continuous monitoring of atmosphericAtmosphere 2021, 12,3 ofradon concentrations combined with statistical anomaly detection strategies to evaluate future seismic dangers [45,52,580], also as low-cost radon monitoring strategies and the application of specialist systems towards the prevention of indoor radon gas exposition dangers, have been reported [614]. 1.3. Aims This study was carried out inside the CARQUAI project (the Italian acronym of Contaminazione Ambientale Radon Qualitdell’Aria Indoor or Environmental Radon Contamination Indoor Air High quality). CARQUAI is an intelligent system utilised for the detection, monitoring and optimiz.