Product Name :
CDC801
Description:
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.
CAS:
192819-27-5
Molecular Weight:
408.45
Formula:
C23H24N2O5
Chemical Name:
3-[3-(cyclopentyloxy)-4-methoxyphenyl]-3-(1, 3-dioxo-2, 3-dihydro-1H-isoindol-2-yl)propanamide
Smiles :
COC1=CC=C(C=C1OC1CCCC1)C(CC(N)=O)N1C(=O)C2=CC=CC=C2C1=O
InChiKey:
DDYUBCCTNHWSQM-UHFFFAOYSA-N
InChi :
InChI=1S/C23H24N2O5/c1-29-19-11-10-14(12-20(19)30-15-6-2-3-7-15)18(13-21(24)26)25-22(27)16-8-4-5-9-17(16)23(25)28/h4-5,8-12,15,18H,2-3,6-7,13H2,1H3,(H2,24,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.Abraxane Data Sheet
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.|Product information|CAS Number: 192819-27-5|Molecular Weight: 408.45|Formula: C23H24N2O5|Chemical Name: 3-[3-(cyclopentyloxy)-4-methoxyphenyl]-3-(1, 3-dioxo-2, 3-dihydro-1H-isoindol-2-yl)propanamide|Smiles: COC1=CC=C(C=C1OC1CCCC1)C(CC(N)=O)N1C(=O)C2=CC=CC=C2C1=O|InChiKey: DDYUBCCTNHWSQM-UHFFFAOYSA-N|InChi: InChI=1S/C23H24N2O5/c1-29-19-11-10-14(12-20(19)30-15-6-2-3-7-15)18(13-21(24)26)25-22(27)16-8-4-5-9-17(16)23(25)28/h4-5,8-12,15,18H,2-3,6-7,13H2,1H3,(H2,24,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.S2116 Formula |Shelf Life: ≥360 days if stored properly.PMID:32083462 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The more detailed information refer to the Compound 6b in the reference 1 (PMID:19256507).|References:|Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4.Products are for research use only. Not for human use.|
