Product Name :
Furanodiene
Description:
Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level.
CAS:
19912-61-9
Molecular Weight:
216.32
Formula:
C15H20O
Chemical Name:
3, 6, 10-trimethyl-4H, 7H, 8H, 11H-cyclodeca[b]furan
Smiles :
CC1CCC=C(C)CC2OC=C(C)C=2CC=1 |c:16,t:4|
InChiKey:
VMDXHYHOJPKFEK-ADUATRDFSA-N
InChi :
InChI=1S/C15H20O/c1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/h6-7,10H,4-5,8-9H2,1-3H3/b11-7-,12-6-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Mupirocin Biological Activity
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level.Vinpocetine Data Sheet |Product information|CAS Number: 19912-61-9|Molecular Weight: 216.PMID:33200674 32|Formula: C15H20O|Chemical Name: 3, 6, 10-trimethyl-4H, 7H, 8H, 11H-cyclodeca[b]furan|Smiles: CC1CCC=C(C)CC2OC=C(C)C=2CC=1 |c:16,t:4||InChiKey: VMDXHYHOJPKFEK-ADUATRDFSA-N|InChi: InChI=1S/C15H20O/c1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/h6-7,10H,4-5,8-9H2,1-3H3/b11-7-,12-6-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Furanodiene (1.4, 4.1, 12.2 uM; 48 hours) is effective in treating human JF 305 pancreatic cancer cells and MCF-7 breast cancer cells xenotranplanted into the zebrafish. Furanodiene has no effect on Pgp related gene (MDR1) expression.|References:|Xiao-Yu Zhu, et al. Sensitization and synergistic anti-cancer effects of Furanodiene identified in zebrafish models. Sci Rep. 2019 Mar 14;9(1):4541.Products are for research use only. Not for human use.|
