Product Name :
PD-1-IN-1
Description:
PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO2015033299A1, compound example 4. PD-1-IN-1 can be used as immune modulator.
CAS:
1673534-76-3
Molecular Weight:
360.32
Formula:
C12H20N6O7
Chemical Name:
(2S,3R)-2-([(1S)-1-3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl-2-carbamoylethyl]carbamoylamino)-3-hydroxybutanoic acid
Smiles :
C[C@@H](O)[C@H](NC(=O)N[C@@H](CC(N)=O)C1=NC(=NO1)[C@@H](N)CO)C(O)=O
InChiKey:
HFOBENSCBRZVSP-LKXGYXEUSA-N
InChi :
InChI=1S/C12H20N6O7/c1-4(20)8(11(22)23)16-12(24)15-6(2-7(14)21)10-17-9(18-25-10)5(13)3-19/h4-6,8,19-20H,2-3,13H2,1H3,(H2,14,21)(H,22,23)(H2,15,16,24)/t4-,5+,6+,8+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Pyridoxamine 5′-phosphate Purity
Additional information:
PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO2015033299A1, compound example 4.Ibudilast Cancer PD-1-IN-1 can be used as immune modulator.PMID:31855395 |Product information|CAS Number: 1673534-76-3|Molecular Weight: 360.32|Formula: C12H20N6O7|Chemical Name: (2S,3R)-2-([(1S)-1-3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl-2-carbamoylethyl]carbamoylamino)-3-hydroxybutanoic acid|Smiles: C[C@@H](O)[C@H](NC(=O)N[C@@H](CC(N)=O)C1=NC(=NO1)[C@@H](N)CO)C(O)=O|InChiKey: HFOBENSCBRZVSP-LKXGYXEUSA-N|InChi: InChI=1S/C12H20N6O7/c1-4(20)8(11(22)23)16-12(24)15-6(2-7(14)21)10-17-9(18-25-10)5(13)3-19/h4-6,8,19-20H,2-3,13H2,1H3,(H2,14,21)(H,22,23)(H2,15,16,24)/t4-,5+,6+,8+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 28.5 mg/mL (79.10 mM; Need ultrasonic and warming).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PD-1 is a co-receptor that is expressed predominantly by T cells. The binding of PD-1 to its ligands, PD-L1 or PD-L2, is vital for the physiological regulation of the immune system.|Products are for research use only. Not for human use.|
